Cabozantinib S-malate

Cabozantinib S-malate

CAS NO.:1140909-48-3
Molecular formula: C ∝₂ H ∝₀ FN ∝ O ₁₀
Molecular weight: 635.6
Purity:>98%

Cabozantinib S-malate | 1140909-48-3 | Cabozantinib malate | Cabozantinib (S) - malate | Cabometyx | Cabozantinib malate (XL184) | Cabozantinib (S-malate) | XL184 | Cometriq | UNII-DR7ST46X58 | BMS907351 | Cabozantinib s-malate [USAN] | Cabozantinib L-malate | DR7ST46X58 | CHEBI: 72319
Specification or purity ≥ 99%
English name Cabozantinib malate (XL184)
The biochemical mechanism of Cabozantinib S malate (XL184 BMS 907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibitors c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively
Storage temperature -20 ° C
Transportation conditions: ultra-low temperature ice pack transportation
Type of action inhibitor
Mechanism of action: hepatocyte growth factor receptor inhibitor

Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively
Cabozantinib S-malate  is an effective multi receptor tyrosine kinase inhibitor with IC50 values of 0.035, 1.3, 4.6, 7, and 11.3 nM, respectively, for inhibiting VEGFR2, c-Met, Kit, Axl, and Flt3.

Supply and Specifications
Multiple specifications are available and a large quantities can be customized;

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