7-Ethyl-10-hydroxycamptothecin Powder
7-Ethyl-10-hydroxycamptothecin (SN-38) Powder is a highly potent antitumor compound, known as the active metabolite of the chemotherapeutic drug Irinotecan (CPT-11). It belongs to the camptothecin family and exhibits strong cytotoxic activity against various types of cancer cells by inhibiting DNA topoisomerase I, an enzyme critical for DNA replication.
📌 Basic Information
Product Name: 7-Ethyl-10-hydroxycamptothecin (SN-38)
Other Names: SN38, CPT-11 active metabolite
CAS Number: 86639-52-3
Molecular Formula: C₂₂H₂₀N₂O₅
Molecular Weight: 392.41 g/mol
Purity: ≥98% (HPLC)
Appearance: Yellow to light orange crystalline powder
Solubility: Soluble in DMSO, methanol; limited solubility in water
Origin: China
Production capacity: 100 tons per month
Transportation packaging: 25/barrel
Certification: ISO9001/Halal/Kosher
Description
|
Product Name |
7-Ethyl-10-hydroxycamptothecin Powder |
|
Heavy Metal |
≤10ppm |
|
Loss on drying |
≤ 5.0% |
Description:
| Feature | Details |
|---|---|
| Name | 7-Ethyl-10-hydroxycamptothecin (SN-38) |
| Function | Topoisomerase I inhibitor, potent anticancer agent |
| Potency | 100–1,000× stronger than irinotecan |
| Applications | Oncology research, drug formulation, cytotoxicity studies |
| Formulation Challenges | Poor solubility, systemic toxicity |
Product Application：
| Area | Description |
|---|---|
| Cancer Drug Screening | Used in preclinical models for assessing tumor cell sensitivity |
| Pharmaceutical Research | Core compound in developing SN-38-based nanodrug carriers |
| Biochemical Assays | Tool compound to study DNA damage and apoptosis pathways |
| Targeted Drug Delivery | Studied in antibody-drug conjugates (ADCs) and micelle systems |
OEM/ODM Service
Greennee offers comprehensive OEM and ODM services to meet your specific needs. We can assist with:
● Private Labeling: Package our products under your own brand name.
● Packaging Design: Create attractive and informative packaging solutions.
Product Packaging and Logistics
Our standard packaging is food-grade sealed bags to ensure product freshness and safety during transportation. We offer various packaging sizes to accommodate different order quantities. We also provide customized packaging options to meet your specific branding and marketing needs. We work with reliable logistics partners to ensure timely and efficient delivery of your orders worldwide.
Storage Situation
Stored in a cool and dry well-closed container, keep away from moisture and strong light / heat.
Shelf Life
two years under well Storage situation and stored away from direct sun light.
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