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Naringenin Powder
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Naringenin Powder

Naringenin Powder

Active Ingredients: Naringenin 98%
Extract part used : peel
CAS NO.: 10236-47-2
Appearance:Off-white powder
Botanical Name:Citrus grandis(L.) Osbeck.
OEM/ODM Tablet,capsules
Origin:China
Production Capacity:100 Tons /Per Month.
Transport Package:25kg/drum and Customized packaging
Certificate:ISO9001/Halal/Kosher,Health certificate and certificate of origin HS Code:2932999099

Description

Product Name

Grapefruit Peel Extract 98% Naringenin

Botanical Name

Citrus grandis(L.) Osbeck.

Extract part used

Peel

Active Ingredients

Naringenin

CAS NO.

10236-47-2

Appearance

Off-white powder

Active Ingredient

Naringin

Mol. Formula

C27H32O14

Test method

HPLC

 

Description

 

Naringenin Powder is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavanone naringenin in humans.

Both naringin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits. Naringin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of selected drug metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug drug interactions in vivo. Ingestion of naringin and related flavonoids can also affect the intestinal absorption of certain drugs, leading to either an increase or decrease in circulating drug levels.

 

Naringenin Powder Function

 

1.It has anticancer effect , can kill various cancer cells .

2.It has protective effect on focal cerebral ischemia reperfusion in rats , and its mechanism may relate with its effective scavenging of free radicals. Naringenin significantly decreased the cerebral water content, reduced the volume of cerebral infarction of the impaired brain hemisphere,lowered the level of MDA and improved the activity of SOD in brain. This shows Naringenin can has protective effect on brain hemisphere .

3. This ingredient can significantly lower the plasma cholesterol concentration and the hepatic cholesterol content .

4. The product has also been shown to reduce hepatitis C virus production by infected hepatocytes (liver cells) in cell culture . This seem to be secondary to Narigenin ability to inhibit the secretion of very low density lipoprotein by the cells.

5. It has bioactive effect on human health as antioidant , free radical scavenger , antisepsis , anti-inflammatory , antispasmodic activity.

 

Naringenin Powder Applications

 

Naringenin Powder finds wide-ranging applications across various industries due to its diverse properties:

● Food and Beverages: Naringenin's bitter flavor profile makes it a valuable ingredient in the formulation of beverages like juices, teas, and energy drinks. It can also be incorporated into baked goods, confectionery, and other food products to enhance their flavor and nutritional value.

● Dietary Supplements: Thanks to its potential health benefits, Naringenin is often included in dietary supplements in the form of capsules, tablets, or powders. These supplements are marketed for various purposes, including antioxidant support, cardiovascular health, and weight management.

● Cosmetics and Personal Care: Naringenin's antioxidant properties are utilized in skincare products to protect against free radical damage and promote healthy skin. It can be found in creams, lotions, and serums designed to improve skin tone and texture.

● Pharmaceuticals: Research suggests that Naringenin may have therapeutic applications in treating various conditions, including inflammation, cancer, and metabolic disorders. It is being investigated for its potential use in pharmaceutical formulations.

 

Certificate of Analysis

 

Product Name:

Naringenin

Plant origin

Citrus grandis(L.) Osbeck.

Batch No:

20190520

Used Part

Peel

Representative QTY:

1000Kgs

Produce date:

May 20,2019

Type of Products

Standardized Powder Extract

Expiration date

May 25,2019

Analysis Date:

May 25,2019

Report Date:

May 25,2019

ITEM

SPECIFICATION

RECULT

 

Description:

Appearance

Odor

Particle size

Bulk Density

Extract Solvents

Off-white powder

Characteristic

100% pass through 80 mesh sieve

45.0g/100mL~65.0 g/100mL

Grain Alcohol

Complies

Complies

Complies

49.3 g/100mL

Complies

 

Identification

Color Reaction

Positive Reaction

Complies

 

Tests:

Loss on drying(5h at 105℃)

Ash(3h at 600℃)

Heavy metals(as Pb)

Arsenic(as AS2O3)

Residual Solvents

<5.0%

<5.0%

<10ppm

<1ppm

Eur. Pharm. 2000

3.05%

3.28%

Complies

Complies

Complies

 

Assay( Naringenin )

>98% by HPLC

98.56%

 

Microbial:

Total bacterial count

Yeast & Mould

Escherichia coli presence

Salmonella

Max.1000cfu/g

Max.100cfu /g

Negative

Negative

Complies

Complies

Complies

Complies

 

Conclusion: Conform with specification.

 

OEM/ODM Service

 

Greennee  offers comprehensive OEM and ODM services, allowing you to customize Naringenin Powder products to meet your specific requirements. We can assist with product development,  packaging, and labeling to create a unique product that aligns with your brand identity.

 

Storage Situation

 

Stored in a cool and dry well-closed container, keep away from moisture and strong light / heat.

 

Shelf Life

 

Two years under well Storage situation and stored away from direct sun light.

 

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Q: What is the recommended dosage for Naringenin Powder?

A: The recommended dosage varies depending on individual needs and the intended application. Consult a healthcare professional for personalized advice.

Q: Is Naringenin Powder safe for everyone?

A: While generally safe, individuals with citrus allergies or those taking certain medications should exercise caution. Consult a healthcare professional before use.

Q: What are the potential side effects of Naringenin Powder?

A: Naringenin is generally well-tolerated. However, excessive consumption may cause gastrointestinal discomfort or interact with certain medications.  

Q: What is the shelf life of Naringenin Powder?

A: When stored properly in a cool, dry place, Naringenin Powder typically has a shelf life of 2 years.

Q: Can Greennee  provide samples of Naringenin Powder?

A: Yes, we offer free samples of 15-20g for your evaluation.

 

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